All the Active Ingredient Drugs
Antifungal, Corticosteroid. Hydrocortisone 10 mg/g, Miconazole (nitrate) 20 mg/g. CREAM: 15 g. Apply top. 1-2 x dly.
Infect. of the skin caus. by dermatophytes
or candida sp. in which inflamm. sympt.
C/I: Hypersens. to miconazole or other
imidazole derive., hydrocortisone;
Tuberculous skin infect., herpes simplex,
vaccinia, all forms of varicella.
Antifungal. Miconazole (nitrate) 20 mg/g. CREAM: 15 g. Skin infects: Apply 1-2 x
dly. for 2-5 wks. Nail infects: Apply 1 x
dly and cover with plaster. Cont. 2
mths. Ear infects: Apply 2 x dly. Cont.
for 2-3 wks.
Skin and nail infects. due to
dermatophytes or candida. Also effect.
against gram +tive cocci, thus used in
Antifungal, Antiinfectives. Miconazole 20 mg/g. ORAL GEL: 40 g.
Oropharyngeal candidosis: Infants
(6-24 mnths): 1.25 mL of gel x 4/d after
meals. Adults, children (>2 yrs old): 2.5
mLof gel x 4/d after meals.
GI tract candidosis: Infants (≥ 6
mnths), Children, Adults: 20 mg/kg/day x 4 divided doses. The daily dose
should not exceed 250 mg x 4/d. See
Oral mycosis (thrush), fungal infect. of the
upper GI tract. Prevent. of oral thrush in
pts receiv. long-termtmt with antibiotics,
steroids, cytotoxic and radiation ther.
C/I: Hypersens. to act. ingred.,exipient,
or other imidazole derive.; infants under
6 mnths. or in those whose swall. reflex
is not yet suffic. developed; pts.with
liver dysfunct.; Coadmin.of the foll.
drugs that are subject to metab. by
CYP3A4: Substr. known to prolong the
QT-interval e.g., astemizole, bepridil,
cisapride, dofetilide, halofantrine,
mizolastine, pimozide, quinidine,
sertindole and terfenadine; Ergot
alkaloids;HMG-CoA reduct.inh. such as
simvastatin and lovastatin; Triazolam,