Mesalazine

8 Drugs classified under this active ingredient

5-Aminosalicylic Acid Derivative. Mesalazine 400 mg, 800 mg.
TABS: 100 x 400 mg. 3-6 tabs. dly. in div.
doses bef. meals.
TABS: 60 x 800 mg. Ulc. colit: Maint.
remission: 1.2-2.4 g dly in div. doses
bef. meals. Chron’s dis: 2.4 g dly in div.
doses bef. meals. Child: No specif.
dose.
Maint. remission in ulcerat. colit., acute
episodes Crohn’s dis.
Ulcerat. proctit.
C/I: Hypersens. to salicylates, liver and
kidney funct. disords., gastric or duod.
ulc., pregn., lact., diabetes.

Aminosalicyclic Acid. Mesalazine 1200 mg.
GAST.-RESIST. PROLONG. REL. TABS.:60.  Adult., include. the elder. (>65 yrs.)
For induct.of remis.: 2.4 - 4.8g (2-4 tabs.) should be taken once dly. The highest dose of 4.8g/d is recomm.  for pts. not respond. to lower doses of mesalazine. When using the highest dose (4.8g/d), the effect of the tmt. should be evaluat.at 8 wks. For mainten. of remis.: 2.4g (two tablets) should be taken once dly.
For the induct. of clinic.& endoscop. remis. in pts. with mild to moder., act. ulcerat. colitis. For maintenan. of remiss.
C/I: History of hypersens.  to salicylates (includ. mesalazine). Sev. renal impair. (GFR <30ml/min/1.73m²) and/or severe hep. impair.

5-Aminosalicylic Acid Derivative. Mesalazine 1 g/ 100 ml.
RETENTION ENEMA: 7 x 1 g/100 ml.
1 dly at bedt. See pt. leaflet.
Crohn’s dis., ulcerat. colit.
C/I: Severe liver/ren. impair., hypersens.
to mesylates/salicylates.

5-Aminosalicylic Acid Derivative. Mesalazine 500 mg, 1 g.
S.R. TABS: 100 x 500 mg, 60 x 1 g. Ulcerat.
colit: Active dis: Up to 4 g dly in div.
doses. Child: Individ. dose. Initial: 50
mg/kg bdy wt. dly in div. doses. Maint:
2 g 1 x dly. Child: Individ. dose: 50 mg/
kg bdy wt. dly in div. doses. Crohn’s dis:
Active dis: Individ. dose: Up to 4 g dly
in div. doses. Child: Individ. dose:
Initial: 50 mg/kg bdy wt. dly in div.
doses. Maint: Individ. dose: Up to 4 g
dly in div. doses as reqd. Child: Individ.
dose: 50 mg/kg bdy wt. dly in div.
doses.
Crohn’s dis., ulcerat. colit.
C/I: Severe liver/ren. impair., hypersens.
to mesylates/salicylates.

5-Aminosalicylic Acid Derivative. Mesalazine 1, 2, 4 g.
SACHETS: 100 x 1 g, 2 g, 4 g. Ulcerat.
colit: Active dis: Up to 4 g dly in div.
doses. Child: Individ. dose. Initial: 50
mg/kg bdy wt. dly in div. doses. Maint:
2 g 1 x dly. Child: Individ. dose: 50 mg/
kg bdy wt. dly in div. doses. Crohn’s dis:
Active dis: Individ. dose: Up to 4 g dly
in div. doses. Child: Individ. dose:
Initial: 50 mg/kg bdy wt. dly in div.
doses. Maint: Individ. dose: Up to 4 g
dly in div. doses as reqd. Child: Individ.
dose: 50 mg/kg bdy wt. dly in div.
doses.
Crohn’s dis., ulcerat. colit.
C/I: Severe liver/ren. impair., hypersens.
to mesylates/salicylates.

5-Aminosalicylic Acid Derivative. Mesalazine 1 g.
SUPPS: 28 x 1 g. 1 supp 1-2 x dly. See
pt. leaflet.
Ulcerat. proctit.
C/I: Severe liver/ren. impair., hypersens.
to mesylates/salicylates.