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  • Macitentan
    1 Drug classified under this active ingredient

    All the Active Ingredient Drugs

    partial basket chart

    Endothelin Receptor Antagonist. Macitentan 10 mg.
    F.C. TABS.: 30. 10 mg ×1/d, with or without food, should be taken every day at the same time.
    Tmt. of PAH, who GROUP I to delay dis. progress. Dis. progress. includ.: death, initiat. of IV or subcutan. prostanoids, or clin. worsening of PAH (decreased 6-min. walk distance, worsened PAH sympt. and need for additional PAH tmt.). The drug also reduced hospitaliz. for PAH.
    C/I: Hypersens., Soya. Preg., WOCBP who are not using reliable contracep., Lact.
    Pts. with severe hep. impair. (with or without cirrhosis).
    Baseline values of hep. aminotransferases (AST and/or ALT>3×ULN).