All the Active Ingredient Drugs
Opioid. Fentanyl (as Citrate) 100, 200, 300, 400, 600, 800 mcg. SUBLING. TABS: 10, 30 x 100 μg, 200 μg,
300 μg , 400 μg, 600 μg, 800 μg.
Initial: 100 μg. subling., not be
swallowed, chewed oe sucked. Titr.
upwards as necess. See lit.
Manag. of breakthr. pain in adult pts using
opioid ther. for chronic cancer pain.
Breakthr. pain is a transient exacerb. of
otherwise control. chronic background
C/I: Hypersens.; Opioid-naïve pts due to
the risk of life-threat. resp. depress.;
Sev. resp. depress. or sev. obstr. lung
cond.; acute or post-oper. pain, incl.
headache/migraine, dental pain, or use in
Opioid. Fentanyl (as citrate) 200, 400, 600, 800, 1200, 1600 mcg/dose. COMPRESSED TAB. ON HANDLE
(lozenge): 30. Initial: 200 μg. To supply
only 6 x 200 μg and to use all units bef. incr. to higher dose. See lit. Unit to be
sucked, not chewed over 15 mins.
Discont: Grad. downward titrat.
Manage. breakthrough cancer pain in pts
16 and older with maligns. who are
already receiv. and tolerant to opioid ther.
for persist. cancer pain.
C/I: Post-op. pain, opioid non-tol.,
hypersens./intol. to fentanyl, anaphylax.
Opioid. Fentanyl 12.5, 25, 50, 75, 100 mcg/hour. TRANSDERMAL 3-DAY MATRIX PATCHES:
5 x 12.5 μg/hr (2.063 mg/patch); 5 x 25 μg/hr (4.125 mg/patch); 5 x 50 μg/hr
(8.25 mg/patch); 5 x 75 μg/hr (12.375
mg/patch); 5 x 100 μg/hr (16.5 mg/
patch). Initial: Depend. on pts. current
cond., intensity of pain, opioid history.
Dose titrat: Initial dose may be incr.
aft. 3 days with patch replacement;
then titrate every 6 days. See lit.
Breakthrough pain may be treated
with supplement. short-act. analges.
Discont. when necess., gradually.
Manage. chron./intract. pain req. opioid
analges. See lit.
C/I: Opioid intoler., post-op. pain, acute
pain, mild-mod. pain. Concurrent with
Narcotic Anesthetic. Fentanyl 0.05 mg/ml. AMPS: 5,50 x 2 ml,10 ml. The
dosage should be individualized.
Vital signs should be routinely
monitored. See lit.
Surg. anesth. and analges. See lit.
Also epidural route for post-op.
pain, adjunct to regional or general
C/I: Hypersens., as with other opiate.
given epidural., should not be given to
pts. exhibiting: severe hemorrh.
or shock, septicemia, disturb. in blood
morphology. See lit.
Opioid Analgesic. Fentanyl 12.5, 25, 50, 75, 100 mcg/hr. TRANSDERMAL PATCHES: 5x12.5µg/hr. (2.1mg/patch), 5x25µg/hr. (4.2mg/patch), 5x50µg/hr. (8.4mg/patch), 5x75µg/hr. (12.6mg/patch), 5x100µg/hr. (16.8mg/patch).
Dosage must be ajust. individ. accord. pt. condit.
Managem. of chron. pain and intractab. pain requir.opioid analgesia. The drug should only be used in pts. who are already receiv. opioid ther., who have demonstrate. opioid tolerance.
C/I: Hypersens. Pts. who did not use an opioid analgesic in the past. Short period pain (e.g., after surgery). Pts. with not chron./ persist. pain. Mild/moder. pain relief. Pts. with sev. breath. problems. Pts. with severe impair. of the CNS funct.(e.g., brain damage). During tmt. with MAO inhib., or within a minim. of 2 wks. of discont. those drugs. Lact. Child. under 2 yrs. of age.
Narcotic Anesthetic. Fentanyl (as citrate) 0.05 mg/ml. AMPS: 10 x 2 ml, 5 x 10 ml.
The dosage should be individ. accord.
to age, bdy wt, physical status, underl.
pathol. cond., use of other drugs, type
of surgery/anesthesia. See lit.
Analges. short trem, dur. anesth. periods;
immed. postoper. period as need arises.;
Narcotic analges. suppl. in gen./region.
anesthesia; For admin. with neurolept. as
anesth. premedic. for the induct. of anesth.
and as an adjunct in the maint. of gen./
region. anesthesia; Anesth. agent with
oxygen in selected high-risk pts; Epidural
route for the postoper. managem. of pain
foll. gen. surgical proced., cesarean
sections, as adjunct to gen. anesthesia.
C/I: Known intoler. to compon., to other
morphinomimetics; Resp. depress.,
obstruct. airways dis.; Concurr.
administer. with MAO-I, or within 2
weeks of their discount.