All the Active Ingredient Drugs
HMG-CoA Reductase Inhibitor, Lipid Modifying Agent. Ezetimibe 10 mg, Atorvastatin 10, 20, 40, 80 mg. F.C. TABS.: 30. Hypercholesterolaemia and/or CHD with ACS History). The pt. should be on an appropriate lipid-lower. diet and should cont. on this diet during tmt. with this drug.
The dose range is 10/10 mg/d. through 10/80 mg/d. The typical dose is 10/10 mg ×1/d. The pt’s. low-density lipoprotein cholesterol (LDL-C) level, CHD status, and response to current cholesterol-lower. ther. should be consid. when starting ther. or adjust. the dose.
The dose should be individual. based on the known efficacy of the various dose strengths of and the response to the current cholesterol-lower. ther. Adjust. of dose should be made at intervals of 4 wks. or more.
HoFH: 10/10-10/80 mg dly. The drug may be used as an adjunct to other lipid-lower. tmts. (e.g., LDL apheresis) in these pts. or if such tms. are unavailab.
May be taken with/without food.
Prevent. of Cardiovasc. Event: Indicat. to reduce the risk of cardiovasc. events in pts. with coron. heart dis.(CHD) and a hist. of acute coron. syndr. (ACS), either previous. treated with a statin or not.
Hypercholesterolaemia: The drug indicat. as adjunct. ther. to diet for use in adult. with prim. (heterozygous famil. and non-famil.) hypercholesterolaemia or mixed hyperlipidaemia where use of a comb. product is appropriate, pts. not appropriat. control. with a statin alone, pts. already treated with a statin and ezetimibe.
Homozyg. Familial Hypercholesterolaemia (HoFH): Indicat. as adjunct. ther. to diet for use in adults with HoFH. Pts. may also receive adjunct. tmts. (e.g., low-density lipoprotein [LDL] apheresis).
C/I: Hypersens. Preg., lact. , and in women of child-bear. potent.
Cholesterol Absorption Inhibitor. Ezetimibe 10 mg. TABS.:30 Adult./ adolesc.(10- 17 yrs.):10mg×1/d with/without food Cholesterol-low. diet should be init. before tmt. initiat. and contin. during the tmt.
Prim. hypercholesterolemia: admin.with a statin or alone. As adjunct. ther.to diet for use in pts. with prim. (heterozygous famil. and non-famil.) hypercholesterolemia. Homozygous famil. hypercholesterolem.: Concom. use with a statin for use in pts. with HoFH .Pts. may also receive adjunct. tmts. (e.g. LDL apheresis). Homozygous sitosterolem. (Phytosterolem.): pts. with homozygous famil. sitosterolem.
C/I: Hypersens. Contom. use with statin, in pts. with hep. impair. Contom. use with statin, in preg./lact.
Cholesterol Absorption Inhibitor. Ezetimibe 10mg. TABS.: 30 ×10mg. 1 tab. ×1/d orally, taken at any time with/ without food. In comb. with statins: both medicines can be taken at the same time.
Primary hypercholesterolemia:
Ezetimibe Teva admin. with a statin or alone are indic. as adjunct. ther. to diet for use in pts. with prim. (heterozygous familial and non-familial) hypercholesterolem.
Homozygous familial hypercholesterolem. (HoFH): Ezetimibe Teva admin. with a statin are indic. for use in pts. with HoFH. Pts. may also receive adjunct. tmt. (e.g. LDL apheresis).
Homozygous sitosterolemia (Phytosterolemia): Ezetimibe Teva is indicated for use in pts. with homozygous familial sitosterolemia.
C/I: Hypersens.
In comb. with statins in pts. with current hep. impair.
In comb. with statins in pregnant of lactat. women.
Cholesterol Absorption Inhibitor. Ezetimibe 10 mg. TABS: 30. 1 tab. dly at any time of day
with or without food.
Prim. hypercholesterem. monother. as
adjunct. to diet in pts. with prim.
hypercholesterem. in whom statin not
appropriate or tolerat., hymozygous
sitosterolem. as adjunct to ther.
C/I: Hypersens., when co-admin. with a
statin, see lit. Ther. in co-admin, with a
statin in pregn. and lact. and active liver
dis. unexplain. persist. elevat. serum
transaminases.
