All the Active Ingredient Drugs
GnRH Antagonist. Elagolix (as sodium) 150 mg, 200 mg. F.C. TABS: 28×150mg, 56×200mg. Init. tmt. with 150 mg×1/d, max. tmt. duration-24 mnths.
Consider initiat. tmt. with 200 mg×2/d max. tmt. duration- 6 mnths., with coexist. cond.- dyspareunia.
Init. tmt. with Elagolix 150 mg×1/d. Use of 200 mg×2/d is not recommended, max. tmt. duration- 6 mnths., with coexist. cond.- moder. hep. impair. (Child-Pugh Class B).
Hep. Impair.: No dosage adjust. of Elagolix is require. in women with mild hep. impair. (Child-Pugh A). Elagolix 150 mg×1/d is recomm. for women with moder. hep. impair. (Child-Pugh B) with the duration of tmt. limited to 6 mnths. Use of Elagolix 200 mg×2/d is not recommend. for women with moder. hep. impair. See lit.
Management of moder.–seve. pain assoc. with endometriosis.
C/I: With Hypersens. Preg. Women with known osteoporosis. Women with sev. hep. impair (Child-Pugh C).