All the Active Ingredient Drugs
Prostaglandin. Dinoprostone 10 mg. S.R. VAG. PESS. (with retrieval system): 5.
Releases 0.3 mg/hr. 1 insert positioned
behind post vag. fornix. If ripening
within 12 hrs., remove. No more than 2
consecutive inserts.
Initiat. and/or continuat. of cervical
ripening in patients at term, from 37th
week of gestation, with bishop score of 6
or less.
Prostaglandin. Dinoprostone 1 mg / 3 g. VAG. GEL: 3 g x 1 mg, 2 mg. Initial: 1 mg. The pt. should remain in supine pos. for at least 30 min. Aft 6 hrs: A second dose of 1 mg or 2 mg, if necessary.
Therapeutic termination of pregnancy, missed abortion.
C/I: Hypersens. Pts. with hypersens. to prostaglandins. Pts. in whom oxytocic drugs are generally contra-indicated or where prolong. contractions of the uterus are consid. inappropriate such as: Cases with a history of Caesarean sec. or major uterin. surg.; Cases where there is evidence of a potent. for obstruct. labour.
In pts. with a past history of, or existing, pelvic inflamm. dis., unless adequate prior tmt. has been instituted.
Pts. with active cardiac, pulmon., renal or hep.dis.
Prostaglandin. Dinoprostone 3 mg. VAG. TAB.: 4. 1 tab. (3 mg) to be inserted high into the posterior fornix. A 2nd tab. may be inserted after 6-8 hrs. if labour is not established. Max. dose 6 mg.
Oxytocic tabs. induc. of labour, especially in pts. with favourable induct. features, when there are no fetal or maternal contra-indications.
C/I: Pts. with a hist. of C- sect. or major uterine surg.
Pts. where there is cephalopelvic disproportion.
Pts. in which fetal malpresentation is present.
Pts. where there is clinical suspicion or definite evidence of pre-existing fetal distress.
Pts. with hist. of difficult labour and/or traumat. delivery.
Pts. with Grand multiparae with over five prev. term pregnancies.
Pts. with ruptured membranes.
In pts. with a past hist. of, or existing, pelvic inflammat. dis., unless adequate prior tmt. has been instituted.
In pts. where there is clinical suspicion or definite evidence of placenta praevia or unexplained vag. bleed. during this pregnancy.
Pts. with active cardiac, pulmon., renal or hepat. dis.
Prostaglandin. Dinoprostone 10 mg/ml. AMPS. (sol. for inj.): 1×0.5 ml. Adult.: Amp. contents must be dilute. Dilute with normal saline or 5% dextrose, to produce a 5mcg/ml sol. The 5 mcg/ml sol. is infused at 2.5 mcg/min. for 30 min. and then maintain. or incr. to 5 mcg/min. The rate should be maintain. for at least 4 hrs. before incr. further. See lit.
Therapeutic termination of pregnancy, missed abortion.
C/I: Hypersens. Pts. with hypersens. to prostaglandins. Pts. in whom oxytocic drugs are generally contra-indicated or where prolong. contractions of the uterus are consid. inappropriate such as: Cases with a history of Caesarean sec. or major uterin. surg.; Cases where there is evidence of a potent. for obstruct. labour. In pts. with a past history of, or existing, pelvic inflamm. dis., unless adequate prior tmt. has been instituted. Pts. with active cardiac, pulmon., renal or hep.dis.
