All the Active Ingredient Drugs
Monoclonal Antibody. Blinatumomab 12.5 mcg/ml. VIAL(concent. for sol. for infus.+ stabilizer sol. for infus.): 1×35mcg. Recommended dose (for adult patients at least 45 kg in weight): 1st Cycle Start. dose Days 1 – 7: 9 mcg/d via cont. infus. Subseq. dose Days 8 – 28: 28 mcg/d via cont. infus. 2 week-tmt. free interval (Days 29 – 42). 2nd cycle & subseq. cycles (Days 1 – 28): 28 mcg/d via cont. infus. See lit.
Tmt. of adult pt. with Philadelphia chromosome-negat. relapsed/ refract.B‑cell precursor ALL. Limitations of use: After fail. of two previous tmts. and with no CNS involvem.
C/I: Hyperses, lact.