Bivalirudin

1 Drug classified under this active ingredient

Thrombin Inhibitor. Bivalirudin 250 mg/vial.
VIALS (pwdr. for I.V. inject.): 1 x 10. I.V.
bolus: 1.0 mg/kg foll. by 4 hr. infus. at
rate of 2.5 mg/kg/hr. Aft. complete
initial 4 hr. infus., addition. I.V. infus.
may be initiat. at 0.2 mg/kg/hr. for up
to 20 hrs. if reqd. Use with aspirin (300
- 325 mg dly). Initiate just prior to
PTCA. May need to reduce dose and
anticoag. status monitored in pts. with
ren. impair.
Unstable ang. undergoing percutan.
translum. coron. angioplasty (PTCA). To
be used with aspirin. See lit. for safety
and effectiveness.
C/I: Known hypersens.