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  • Angiomax
    / Medison


    Active Ingredient
    Bivalirudin 250 mg/vial

    Status in Israel
    RX

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft

    Vial

    10 X 250 mg/vial

    not in the basket chart

    Dosage

    For patients who do not have HIT/HITTS
    PCI/PTCA: 0.75 mg/kg intravenous (IV) bolus dose followed immediately by a 1.75 mg/kg/h IV infusion for the duration of the procedure.
    PCI: 0.75 mg/kg IV bolus dose followed immediately by a 1.75 mg/kg/h IV infusion for the duration of the procedure.
    For patients with Consider extending duration of infusion post-procedure
    up to 4 hours.
    See prescribing information for full details.


    Indications

    Anticoagulant in patients with unstable angina undergoing percutaneous transluminal coronary angioplasty (PTCA). It is intended for use with aspirin and has been studied only in patients receiving concomitant aspirin. The safety and effectiveness have not been established when used in conjunction with platelet inhibitors other than aspirin, such as glycoprotein IIb/IIa inhibitors. The safety and effectivenss have not been established in patients with unstable angina who are not undergoing PTCA or in patients with other acute coronary syndromes.


    Contra-Indications

    Known hypersensitivity to any component. Active major bleeding. Intramuscular administration.


    Special Precautions

    Patients with heparin-induced thrombocytopenia/heparin-induced thrombocytopenia/thrombosis syndrome (HIT/HITTS) undergoing PTCA.


    Side Effects

    Back pain, nausea, headache, hypotension.


    Drug interactions

    See prescribing information for full details.


    Manufacturer
    medicines Company USA
    Licence holder
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