All the Active Ingredient Drugs
Antibiotics. Amphotericin B 5mg/ml. VIAL (Concent. for susp.for infus.):
10×20ml. IV infus. at 5 mg/kg at a rate of
2.5 mg/kg/hr. See lit.
Tmt. of sev. invas. candidiasis. As 2nd line
therapy for the tmt. of sev. syst. fungal
infec. in pts. who have not responded to
conventional amphotericin B or other
syst. antifung. agents, in those who have
renal impair. or other contra-indic. to
conventional amphotericin B, or in pts.
who have developed amphotericin B
As 2nd line tmt. for invas. aspergillosis,
cryptococcal meningitis and
disseminated cryptococcosis in HIV pts.,
fusariosis, coccidiomycosis, zygomycosis
Antifungal. Amphotericin B 50 mg/vial. VIALS: 10. 1 mg/kg bdy. wt. dly. incr.
step-wise as reqd. I.V. infus. over 30-60
mins. See lit.
Severe system. and/or deep mycoses,
where toxicity (partic. nephrotox.)
precludes use of convent. ther., syst. fung.
infects. in immunocomp. pts., prim. ther.
visceral leishman. in immunocompetent
pts., immuno-compromised pts. e.g. HIV pos.