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  • Metronidazole
    / Lapidot


    Active Ingredient
    Metronidazole 500 mg / 100 ml

    Status in Israel
    RX

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft

    Solution for Infusion

    EP: 10 X 100 ml

    not in the basket chart 88201

    Solution for Infusion

    GV: 20 X 100 ml

    not in the basket chart 88200

    Solution for Infusion

    20 X 0.5 g

    not in the basket chart 30099 13648

    Related information


    Dosage

    Unless otherwise directed the following dosage guidelines are recommended:
    Adults and children over 12 years: Maintenance dose: 
    Approximately 7.5 mg Metronidazole/kg body weight over one hour every 8 hours, corresponding to 100 ml (500 mg) Metronidazole injection for a 70 Kg adult.
    Loading dose: 15 mg/kg infused over one hour (approximately 1 g for 70 kg adult): A maximum of 1.4 g should not be exceeded during 24 hours. Safety and effectiveness in children have not been established. In renal insufficiency the dose interval is to be extended to 12 hours.
    In severe hepatic disease plasma metronidazole levels have to be monitored. The usually recommended dose may eventually have to be reduced.


    Indications

    Prophylaxis and treatment of anerobic bacteria and protozoa.


    Contra-Indications

    Hypersensitivity, 1st trimester pregnancy, patients with trichomonas.
    See prescribing information for full details.


    Special Precautions

    See prescribing information for full details.


    Side Effects

    See prescribing information for full details.


    Drug interactions

    Alcohol, barbiturates, coumarin anticoagulants, cimetidine, phenytoin, disulfiram, lithium.


    Manufacturer
    B. Braun Melsungen AG
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