Presentation and Status in Health Basket
The usual standard dose is once a day at the evening. 2-5 weeks may pass until the effect of the medicine will be noticed.
Mild to moderate acne vulgaris, particularly inflammatory lesions.
Hypersensitivity to the active substances, lincomycin or to any of the excipients.
Contact with the mouth, eyes, lips and mucous membranes or areas of irritated or broken skin should be avoided. Application to sensitive areas of skin should be made with caution. In case of accidental contact, rinse well with water.
During the first weeks of treatment, an increase in peeling and reddening will occur in most patients. Depending upon the severity of these side effects, patients can use a non-comedogenic moisturizer, temporarily reduce the frequency of application of this agent or temporarily discontinue use; however, efficacy has not been established for less than once daily dosing frequencies.
The gel should be used with caution in patients with a history of regional enteritis or ulcerative colitis, or a history of antibiotic-associated colitis.
The gel should be used with caution in atopic patients, in whom further skin drying may occur.
Concomitant topical acne therapy should be used with caution because a possible cumulative irritancy may occur, which sometimes may be severe, especially with the use of peeling, desquamating, or abrasive agents.
If severe local irritancy (e.g. severe erythema, severe dryness and itching, severe stinging/burning) occurs, the gel should be discontinued.
As benzoyl peroxide may cause increased sensitivity to sunlight, sunlamps should not be used and deliberate or prolonged exposure to sun should be avoided or minimized. When exposure to strong sunlight cannot be avoided, patients should be advised to use a sunscreen product and wear protective clothing.
If a patient has sunburn, this should be resolved before using the gel.
If prolonged or significant diarrhea occurs or the patient suffers from abdominal cramps, treatment with this Gel should be discontinued immediately, as the symptoms may indicate antibiotic-associated colitis.
Suitable diagnostic methods, such as the determination of Clostridium difficile and toxin and, if necessary, colonoscopy should be employed and treatment options for colitis considered.
The product may bleach hair or colored fabrics. Avoid contact with hair, fabrics, furniture or carpeting.
Resistance to clindamycin: Patients with a recent history of systemic or topical clindamycin or erythromycin use are more likely to have pre-existing anti-microbial resistant Propionibacterium acnes and commensal flora.
Cross-resistance: Cross-resistance may occur with other antibiotics such as lincomycin and erythromycin when using antibiotic monotherapy.
Burning sensation, erythema.
Please refer to the license holder for further details.
Storage: Store at 2-8ºC.