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    / Unipharm


    Active Ingredient
    Donepezil HCl 5 mg, 10 mg

    Status in Israel
    RX

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft

    Tablets

    28 X 5 mg

    partial basket chart 20958 13149

    Tablets

    28 X 10 mg

    partial basket chart 20959 13362

    Related information


    Dosage

    One tablet of 5 mg every night. After one month, the doctor may increase to 10 mg per day (to take at night).
    The maximal dosage is 10 mg per day.


    Indications

    Mild to moderately severe Alzheimer’s dementia.


    Contra-Indications

    Hypersensitivity to components, or piperidine derivatives.


    Special Precautions

    Likely to exaggerate succinylcholine-type muscle relaxation during anesthesia, may have vagotonic effects on heart rate, in patients with “sick sinus syndrome” or other supraventricular cardiac conduction conditions. Patients should be monitored closely for symptoms of active or occult gastrointestinal bleeding.


    Side Effects

    Nausea, diarrhea, insomnia, vomiting, muscle cramp, fatigue and anorexia, often of mild intensity and transient.


    Drug interactions

    Phenytoin, carbamazepine, dexamethasone, rifampicin, phenobarbital.


    Manufacturer
    Trima Israel Pharmaceutical Products Maabarot Ltd. Israel
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