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  • Vinca Alkaloid
    7 Drugs classified under this drug class


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    Blastovin PF
    Salomon, Levin & Elstein Ltd
    RX
    not in the basket chart
    Blastovin PF

    Vinca Alkaloid. Vinblastine Sulphate 1 mg/ml.
    VIALS: 10 mg. I.V. inject. Initial: Adults:
    Single dose 0.1 mg/kg (3.7 mg/m2) 1 x
    wkly, follow. by leukocyte count. Child:
    Single dose 2.5 mg/m2, follow. by
    leukocyte count. Maint. ther., liver, ren.
    funct. disords., combinat. ther: See lit.
    Tmt. of follow. neoplasms, alone/in
    conjunct. with other oncolyt. drugs: Freq.
    respons. maligns: General. Hodgkin’s dis.
    (stages III and IV, Ann Arbor modific. of Rye
    staging system); non-Hodgkin’s
    lymphoma, reticulum-cell sarcoma,
    lymphosarcoma, mycosis fungoides,
    neuroblastoma, Histiocytosis X. Less freq.
    respons. maligns: Choriocarcinoma resist.
    to other chemotherapeut. agents,
    embryonal carcinoma of the testis,
    carcinoma of the breast, unrespons. to
    approp. endocrine surrg and hormonal
    ther.
    C/I: Hypersens. to vinblastine or other
    vinca-alkaloids, excipients. Leukopen.
    not relat. to tumor, severe uncontroll.
    infect. Such infects. must first be
    controll. with antiseptics/antibiotics bef.
    admin. vinblastine, intrathecal admin.
    vinblastine.

    Javlor
    Perrigo
    RX
    not in the basket chart
    Javlor

    Vinca Alkaloid. Vinflunine (as Ditartrate) 25 mg / ml.
    VIALS: 2, 4, 10 ml. IV use, dosage must
    be adjust. individ.foresch pt. accord.
    gener. cond., hep./ren. funct., blood
    counts.
    As a monother. for the tmt. of adult pts.
    with advanc.,metast. transit. cell carcin. of
    the urothelial tract after fail. of a prior
    platinum-contain. reg.
    Efficacy and safety of have not been
    stud.in pts. with Performance Status ≥ 2.
    C/I: Hypersens. to the act. subst., other
    vincaalkal. Recent (within 2 weeks) or
    curr. sev. infec. Baseline ANC <1,500/
    mm3 for the 1st administ., baseline ANC
    <1,000/mm³ for subseq. admin

    Navelbine 10 mg/ml Concentrate for Solution for Infusion
    Perrigo
    RX
    partial basket chart
    Navelbine 10 mg/ml Concentrate for Solution for Infusion

    Vinca Alkaloid. Vinorelbine 10mg/ml.
    VIALS (conc. sol. for. infuse.): 1 ml, 5 ml x
    10 mg/ml. For I.V. admin. Dosage must be individ. adjust. for each pt. accord. to indic. and pt. med. cond.
    Non small cell lung cancer, advanced
    breast cancer, hormone refract.
    Prostatecancer, espec. in comb. with low
    dose oral cortico-ther. or estramustine.
    C/I: Known hypersens. Vinorelbine or
    other vinca alk.
    Neutrophil count < 1500/mm3 or sev.
    infec. curr., recent (within 2 weeks).
    Platelet count < 100000/mm3. comb.
    with yellow fev.vac. Preg., lact.
    Addit. only for oral use prepar.: Dis.
    signific. affect. absorp. Prev. sign.surg.
    resec. of stomach, small bow.
    Sev. hep. insuffic. Pts. require.g longterm
    oxygen ther.

    Navelbine 20 mg, 30 mg Capsules
    Perrigo
    RX
    partial basket chart
    Navelbine 20 mg, 30 mg Capsules

    Vinca Alkaloid. Vinorelbine 20 mg, 30 mg.
    CAPS: 1 x 20 mg, 30 mg. As single agent,
    to be tak en with food. 1st 3 admins: 60
    mg/m2 bdy surface area 1 x wkly.
    Subseq. admins: Incr. to 80 mg/m2 1 x
    wkly except when neutrophil count
    dropped. Dosage must be individ.
    adjust. for each pt. accord. to indic. and
    pt. med. cond.
    Non small cell lung cancer, advanced
    breast cancer.
    C/I: Known hypersens. Vinorelbine or
    other vinca alk.
    Neutrophil count < 1500/mm3 or sev.
    infec. curr., recent (within 2 weeks).
    Platelet count < 100000/mm3. comb.
    with yellow fev.vac. Preg., lact.
    Addit. only for oral use prepar.: Dis.
    signific. affect. absorp. Prev. sign.surg.
    resec. of stomach, small bow.
    Sev. hep. insuffic. Pts. require.g longterm
    oxygen ther.

    Vincristine
    Salomon, Levin & Elstein Ltd
    RX
    partial basket chart
    Vincristine

    Vinca Alkaloid. Vincristine Sulphate 1 mg/ml.
    VIALS: 1 ml, 2 ml, 5ml. See lit.
    Acute leukem., malign. lymphomas (incl.
    Hodgkin’s dis.), lympho-sarcoma,
    reticulum cell, sarcoma, neuroblastoma,
    Wilm’s tumor, rhabdomyosarcoma.

    Vinorelbin “Ebewe” 10 mg/ml
    Novartis
    RX
    partial basket chart
    Vinorelbin “Ebewe” 10 mg/ml

    Vinca Alkaloid. Vinorelbine (as tartrate) 10 mg/ml.
    VIALS: 1 x 10 mg/ml; 1 x 50 mg/5 ml. I.V.
    use. Adjust accord. indicat., gen. cond.,
    hepat./ren. funct., concurr. chemother.,
    blood counts.
    Non-small cell lung cancer, advanced
    breast cancer, hormone-refract. prostate
    cancer espec. in comb. with low dose oral
    corticoid ther. or Estramustin.
    C/I: Hypersens., neutrophil counts below
    2,000/mm3, severe current/recent
    infect., pregn., lact. Intrathecal admin.

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