All the Drug Class Drugs
Selective α1 Blocker. Doxazosin (as mesylate) 1 mg, 2 mg, 4 mg. TABS: 30x1mg.
CAPLETS: 30x2mg, 4mg.
Hypertens.: Once dly. regimen: the initial dose is 1mg. Dosage may then be incr. to 2mg after an addit. one or two wks. of ther. and thereafter, if necessary to 4mg. The majority of pts. who respond to doxazocin will do so at a dose of 4mg or less. Dosage can be further incr. if necessary to 8mg or the max. recomm. dose of 16mg.
Benign prostatic hyperplasia: Init. dosage is 1mg given once dly. Depend. on the individ. pt's. urodynamics and BPH symptomatology dosage may then be incr. to 2mg and thereafter to 4mg and up to the max. recomm. dose of 8mg. The recomm. titrat. interval is 1-2 wks. The usual recomm. dose is 2-4mg dly.
For dosage in ren./hep. impair./ elderly/paed.: see lit.
For the tmt. of benign prostat. hypertrophy.
C/I: Hypersens. to the active subst. or other types of quinazolines (e.g. prazosin, terazosin). Pts. with a history of orthostatic hypotens. Pts. with benign prostatic hyperplasia and concom. congestion of the upper urin. tract, chron. UTI or bladder stones. Pts. with hypotension (for benign prostat. hyperplasia only). Monother. in pts. with either overflow bladder or anuria with or without progressive renal insuffic.
Selective α1 Blocker. Terazosin (as monohydrochloride dihydrate) 2 mg. TABS: Starter Pack: 7 x 1 mg, 2 mg. 28 x 5 mg, 10 mg. Initial: 1 x 1 mg tab 1 x
dly at bedt. Incr. step-wise to 2 mg, 5 mg
or 10 mg 1 x dly to achieve desired
Sympt. tmt. urinary obstruct. caused by
BPH, mild to mod. hypertens.
Selective α1 Blocker. Terazosin HCl dihydrate 5 mg. TABS: 30 x 5 mg. If discont. for
several days, tmt. should be reinstitut.
start. initial dos. regimen. BPH: Initial:
1 mg at bedt., not to be exceed.
Monitor during initial admin., risk of
severe hypotens. Incr. stepwise to 2
mg, 5 mg or 10 mg 1 x dly. 10 mg 1 x
dly gen. req. for clin. response. Cont.
for min. 4-6 wks. to assess benefic.
response. Caution dur. concom. admin.
other antihypertens., espec. verapamil,
to avoid hypotens. Dose reduct./
retitrat. may be necess. Hypertens:
Adjust dose (12/24 hrs) acc. pts. BP
response. Initial: 1 mg at bedt., not to
be exceed. Monitor during initial
admin., risk of severe hypotens. May
be slowly incr., 1 mg-5 mg 1 x dly,
some pts. 20 mg/day. Monitor BP at
end of dos. interval; also 2-3 hrs. after
dosing for excessive hypotens.
response. If response is diminished at
24 hrs, consider incr. dose or 2 x dly
reg. Except initial dose, admin. in
Symptomat. tmt. urinary obstruct.,
caused by BPH. Mild-mod. hypertens.
C/I: Known hypersens.