All the Active Ingredient Drugs
Selective α1 Blocker. Doxazosin (as mesylate) 1 mg, 2 mg, 4 mg. TABS: 30x1mg.
CAPLETS: 30x2mg, 4mg.
Hypertens.: Once dly. regimen: the initial dose is 1mg. Dosage may then be incr. to 2mg after an addit. one or two wks. of ther. and thereafter, if necessary to 4mg. The majority of pts. who respond to doxazocin will do so at a dose of 4mg or less. Dosage can be further incr. if necessary to 8mg or the max. recomm. dose of 16mg.
Benign prostatic hyperplasia: Init. dosage is 1mg given once dly. Depend. on the individ. pt's. urodynamics and BPH symptomatology dosage may then be incr. to 2mg and thereafter to 4mg and up to the max. recomm. dose of 8mg. The recomm. titrat. interval is 1-2 wks. The usual recomm. dose is 2-4mg dly.
For dosage in ren./hep. impair./ elderly/paed.: see lit.
For the tmt. of benign prostat. hypertrophy.
C/I: Hypersens. to the active subst. or other types of quinazolines (e.g. prazosin, terazosin). Pts. with a history of orthostatic hypotens. Pts. with benign prostatic hyperplasia and concom. congestion of the upper urin. tract, chron. UTI or bladder stones. Pts. with hypotension (for benign prostat. hyperplasia only). Monother. in pts. with either overflow bladder or anuria with or without progressive renal insuffic.