All the Drug Class Drugs
Second Generation (Atypical) Antipsychotic. Cariprazine as HCl salt 1.5, 3, 4.5, 6 mg. CAPS.:30. The recom. start. dose of cariprazine is 1.5 mg ×1/d. Thereafter the dose can be incr. slowly in 1.5 mg increm. to a max. dose of 6 mg/d, if needed. The lowest effective dose should be maint. accord. to the clinical judgement.
Pts. with ren. impair.: No dose adjust. is required in pts. with mild to moder. renal impair. (CrCl) ≥ 30 mL/min and < 89 mL/min). Not recom. in pts. with severe renal impair.( (CrCl)<30 mL/min).
Pts. with hep. impair.: No dose adjust. is required in pts. with mild-moder. hep. impair. (Child-Pugh score between 5-9). Not recom. in pts. with severe hep. impair. (Child-Pugh score 10-15).
Elderly: pts. aged ≥65 yrs.: Dose selection should be more cautious.
Ped. pts.: No data is available.
Tmt . of schizophrenia in adult pts.
Concom. admin. of strong or moderate CYP3A4 inhib. and inducers. See Lit.