• Home
  • A-B index
  • Pharmacological Index
  • Drug Classes
  • Active Ingredients
  • Companies
  • News
  • Nitrogen mustard analogues
    1 Drug classified under this drug class


    All the Drug Class Drugs

    BENDAMUSTINE MEDAC 25, 100 mg
    Tzamal
    RX
    not in the basket chart
    BENDAMUSTINE MEDAC 25, 100 mg

    Nitrogen mustard analogues. Bendamustine Hydrochloride 25,100 mg.
    VIAL(Pwdr. for concentrate for sol. for IV infus.):1×25,100 mg.
    Monother. for CLL 100 mg/m² bdy. surface area bendamustine HCl on days 1 and 2; every 4 wks. up to 6 times.
    Monother. for indolent non-Hodgkin’s lymphomas refract. to rituximab
    120 mg/m² bdy. surface area bendamustine HCl on days 1 and 2;
    every 3 wks. for at least 6 times.
    Follicular non-Hodgkin’s lymphoma: Comb. with rituximab
    The dose is 90 mg/m² body surface area bendamustine HCl on days 1 and 2
    plus 375 mg/m² rituximab on day 1; repetition every 4 wks. See lit.
    1st -line of CLL (Binet stage B or C) in pts. for whom fludarabine comb. chemother. is not appropiate. Indolent non-Hodgkin’s lymphomas as monother.in pts., who have progress. during or within 6 mnths. follow. tmt. with rituximab or a rituximab contain. regimen. Follicular non-Hodgkin’s lymphoma as 1st  line tmt. in comb. with rituximab.
    C/I: Hypersens.
    Lact.
    Sev. hep. impair. (serum bilirub. > 3.0 mg/dl).
    Jaundice.
    Severe bone marrow suppres. and severe blood count alterations (leukocyte and/or platelet values dropped to < 3,000/μl or < 75,000/μl, respectively).

    CLOSE