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  • Cortisol Synthesis Inhibitor
    1 Drug classified under this drug class

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    Metopirone 250
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    Metopirone 250

    Cortisol Synthesis Inhibitor. Metyrapone 250 mg.
    CAPS: 50. Single-dose short test: 30
    mg/kg at midnight with milk. Multidose
    test: 500-700 mg every 4 hrs. for
    24 hrs. Child: 15 mg/kg with minimum
    dose of 250 mg every 4 hrs. for 6 doses.
    Diagnostic test second. adrenocortical
    insuffic., tmt. resist. edema assoc. with
    incr. aldosterone secretion.
    C/I: Hypersens., manifest primary
    adreno-cortical insuffic.