All the Drug Class Drugs
cmv. Letermovir 20 mg, 120 mg, 240 mg, 480 mg. FC Tabs 28 X 240 mg or 480 mg
Sachet 30 X 20 mg / 120 mg
To be started after HSCT. Letermovir may be started on the day of transplant and no later than 28 days post-HSCT. Letermovir may be started before or after engraftment. Prophylaxis with letermovir should continue through 100 days post-HSCT. Recommended dose is 480 mg 1/d.
Ped. pts.: 15 < BW< 30 : 240 mg/d
7.5 <BW< 15: 120 mg/d
5 <BW< 7.5: 80 mg/d
See full prescript. info. re. coadmin. with Cyclosporine.
For prophylaxis of cytomegalovirus (CMV) reactivation and dis. in adult and paed. pts weighing at least 15 kg who are CMV-seropositive recipients [R+] of an allogeneic haematopoietic stem cell transplant (HSCT)
C/I: Hypersens. Concom. admin with pimozide, ergot alkaloids, St. John’s wort (Hypericum perforatum). When letermovir is combined with cyclosporine: Concom. use of dabigatran, atorvastatin, simvastatin, rosuvastatin or pitavastatin.
