All the Drug Class Drugs
Cardiac Glycoside. Digoxin 0.25 mg. TABS.: 50 x 0.25 mg. The dose must be
tailored individ. for each pt. accord. to
age, lean bdy. wt. and renal func.
Adults, child. over 10 yrs: Rapid oral
admin.: 0.75 - 1.5 mg as a single dose.
Slow oral admin.: 0.25 - 0.75 mg dly for
1 week followed by a suitable mainten.
dose. See lit. Children < 10 yrs.: See lit.
Card. fail.: tmt. of chron. card. fail. where the
principal cause is syst. dysfunc. The greatest
therap. benefit is achieved in pts. with
ventric. dilatation.Card. fail. accompanied
by atrial fibril. Supraventric. arrhythmias:
tmt. of certain supraventric. arrhythmias,
particul. atrial fibril. and flutter, where its
principal beneficial effect is to reduce the
ventric. rate.
C/I: Hypersens. or to other digitalis
glycosides; Pts. with intermit. compl. heart
block or 2nd –deg. AV block, especially if
there is a hist. of stokes-adams synd. Pts.
with arrhyth. caused by card. glycos. intox.
Pts. with supraventr. arrhyth. assoc. with an
accessory atrioventr. pathway, as in WPW
synd. , unless the electrophys. character. of
the accessory pathway and any possible
harmful eff. of Digoxin on these character.
have been evaluated. Known or suspect.
accessory pathway to be present and there
is no hist. of prev. supravent. arrhyth. Pts.
with ventr. tachycar. or ventric. fibril. Pts.
with hypertroph. obstruct. cardiomyopat.,
unless there is concom. atrial fibril. and HF,
but even then caution should be exercised.
