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  • Bradykinin B2 Receptor Antagonist
    1 Drug classified under this drug class

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    Bradykinin B2 Receptor Antagonist. Icatibant (as acetate) 30 mg / 3 ml.
    SYR. (Sol. for S.C. inj.).: 1. One S.C. inj. of Icatibant (3 ml/30 mg), as soon as signs of attack are detected (e.g. swelling of the skin, especially in the area of the face and neck, or increas. abdom. pain).
    If the condition is not improved in 6 hrs., another 3 ml dose may be admin.
    If there is still no improv., a 3rd dose may be admin. after another 6 hrs.
    No more than 3 doses in 24 hrs. and no more than 8 inj. of icatibant in one month. Child.& adolesc. 2-17 yrs. of age:  1 ml up to a max. of 3 ml, inject. S.C. accord. to bdy. wt. (one syr.  contains 3 ml), as soon as signs of angioedema attack develop (e.g. incr.swell. of the skin, especially in the area of the face and neck, or increas. abd. pain)See lit.
    Symptomat. tmt .of acute attacks of hereditary angioedima (HAE) in adult., adolesc. & child. aged 2 yrs. and older, with C1-esterase-inhib. defic.
    C/I: Hypersens.