BCL-2 Inhibitor

1 Drug classified under this drug class

BCL-2 Inhibitor. Venetoclax 10, 50, 100 mg.
F.C. TABS.: Dosage should be ajust. individ. See lit.
Tmt. of pts. with Chron. Lymphoc. Leukem./Small Lymphoc. Lymphoma with or without 17p deletion, who have received at least one prior ther.
Acute Myeloid Leukem.: in comb. with a hypomethylating agent/comb. with low dose cytarabine is indicated for newly diagnosed pts. with AML who are ineligible for intensive chemother.
C/I: Concom. use with strong CYP3A inhib. at init. and during ramp-up phase is contraind. in pts. with CLL/SLL due to the potent. for incr. risk of tumor lysis syndr. Concom. use with St. John’s wort.