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  • Antithrombotic Agent
    1 Drug classified under this drug class


    All the Drug Class Drugs

    Defitelio®
    Medison
    RX
    partial basket chart
    Defitelio®

    Antithrombotic Agent. Defibrotide 80 mg/ml.
    VIAL (Concentrat. for sol. for infus.):  The recomm. dose is 6.25 mg/kg bdy wt. every 6 hrs. (25 mg/kg/d).
    There is limited effic. and safet. data on doses above this level and consequen. it is not recom. to incr. the dose above 25 mg/kg/d.
    The tmt. should be admin. for a min. of 21 d. and cont. until the sympt. and signs of sev. VOD resolve. See lit.
    Tmt. of sev. hepat. veno-occlusive dis. (VOD) also known as sinusoid. obstruct. syndr. (SOS) in haematopoietic stem-cell transplantat. (HSCT) ther.
    It is indicated in adult. and in adolesc., child. and infant. over 1 mnth. of age.
    C/I: Hypersens. Concom. use of thrombolytic ther.

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