• Home
  • A-B index
  • Pharmacological Index
  • Drug Classes
  • Active Ingredients
  • Companies
  • News
  • Antithrombotic Agent
    1 Drug classified under this drug class

    All the Drug Class Drugs

    partial basket chart

    Antithrombotic Agent. Defibrotide 80 mg/ml.
    VIAL (Concentrat. for sol. for infus.):  The recomm. dose is 6.25 mg/kg bdy wt. every 6 hrs. (25 mg/kg/d).
    There is limited effic. and safet. data on doses above this level and consequen. it is not recom. to incr. the dose above 25 mg/kg/d.
    The tmt. should be admin. for a min. of 21 d. and cont. until the sympt. and signs of sev. VOD resolve. See lit.
    Tmt. of sev. hepat. veno-occlusive dis. (VOD) also known as sinusoid. obstruct. syndr. (SOS) in haematopoietic stem-cell transplantat. (HSCT) ther.
    It is indicated in adult. and in adolesc., child. and infant. over 1 mnth. of age.
    C/I: Hypersens. Concom. use of thrombolytic ther.