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  • Antimetabolite (antifolate)
    1 Drug classified under this drug class

    All the Drug Class Drugs

    Eli Lilly
    partial basket chart

    Antimetabolite (antifolate). Pemetrexed 100 mg, 500 mg.
    VIAL: 1X 100 mg, 500 mg. Comb. use
    with cisplatin: 500 mg/m2 I.V. over 10
    mins. on day 1 of each 21-day cycle.
    Recommend. dose cisplatin: 75 mg/m2
    I.V. over 2 hrs. begin. 30 mins. aft. end
    of Alimta admin.
    Monother: 500 mg/m2 IV over 10 mins.
    on the 1 day of each 21-day cycle. See
    In comb. with cisplatin for tmt.: malignant
    pleural mesothelioma whose dis.
    unresectable or otherwise not candidates
    for curative surg.; first line tmt. locally
    advanced/ metastat. non-small cell
    lungcancer other than predom. Squamous
    cell histology. As monother: in local.
    advanced/ metastat. non-small cell lung
    cancer other than predom. squamous cell
    histology histology in patients whose dis.
    has not progressed immediately following
    platinum-based chemotherapy; second
    line tmt. locally advanced/metastat.
    nonsmall cell lung cancer, other than
    predom. squamous cell histology.
    C/I: Hypersens., lact., concom. yellow
    fever vaccine.