All the Drug Class Drugs
Anti-Parathyroid Agent. Cinacalcet (as HCl) 30, 60, 90 mg. TABS.: 30×60, 30 mg, 28×90 mg. Hyperparathyroidism (usual start. dose): 30 mg ×1/d.
Parathyroid cancer, primary hyperparathyroidism (usual start. dose):30 mg×2/d.
Tmt. of secondary HPT in ESRD on mainten. dialysis ther. May be used as part of a therap. regimen includ. phosphate binders and/or Vit. D sterols, as appropriate. Reduct. of hypercalcaemia in pts. with parathyroid carcinoma. Reduct. of hypercalcaemia in pts. with: Parathyroid Carcinoma, Primary HPT for whom parathyroidectomy would be indicated on the basis of serum calcium levels (as defined by relevant tmt. guidelines), but in whom parathyroidectomy is not clinic. appropriate or contraindic.
C/I: Hypersens.
Anti-Parathyroid Agent. Cinacalcet 30, 60, 90 mg. F.C. TABS.: 14, 28, 30, 84. Usual start. is 30 mg, once per day. Parathyroid cancer/ prim. hyperparathyroidism: usual start. dose is 30mg×2/d with or shortly after food.
Tmt. of second. HPT in pts. with ESRD on maint. dialysis ther. As part of a therap. regimen includ. phosphate binders and/ or vitamin D sterols, as appropriate. Reduct. of hypercalcaemia in pts. with:
Parathyroid carcinoma, Primary HPT for whom parathyroidectomy would be indicated on the basis of serum calcium levels (as defined by relevant treatment guidelines), but in whom parathyroidectomy is not clinical. appropriate or is contraindicated.
C/I: Hypersens.
Anti-Parathyroid Agent. Cinacalcet 30, 60, 90 mg. F.C. TABS: 14, 28, 84 x 30 mg, 60 mg, 90
mg. With food/shortly aft. meal, whole
and not div. Adults only. Second.
hyperparathyroidism: Initial: 30 mg 1 x
dly. Titrate every 2-4 wks to max. 180
mg 1 x dly. PTH levels to be assessed at
least 12 hrs. aft. dos. See lit.
Parathyroid carcinoma and primary
hyperparathyroidism: Initial: 30 mg 2 x
dly. Titrate every 2-4 wks as foll:
Sequentially: 30 mg 2 x dly; 60 mg 2 x
dly; 90 mg 2 x dly and 90 mg 3-4 x dly
as req. to reduce serum calc. conc. to
below upper limit of normal. Max: 90
mg 4 x dly.
Tmt. second. hyperparathyroidism (HPT)
in end-stage ren. dis. (ESRD) on maint.
dialysis as part of ther. regimen incl.
phosphate binders and/or vit. D steroids
(as appropriate). Reduct. hypercalcem. in
parathyroid carcinoma and primary HPT
for whom parathyroidectomy would be
indicated based on serum calc. levels
(defin. by relev. treat. guide.), but in whom
parathyroidectomy is not clinic. approp. or
is contraind.
C/I: Hypersens.
