Androgen Biosynthesis Inhibitor

3 Drugs classified under this drug class

Androgen Biosynthesis Inhibitor. Abiraterone Acetate 250 mg , 500 mg.
TABS.: 250 mg x 120 , 500 mg x 60.
Intended  for male pts. only. 1,000 mg (4×250mg tabs. or 2x500mg tabs.) once dly.
 1. in combin. with prednisone for metast. castrat.-resist. prostate cancer.
2. For newly diag. high risk metast. hne. sensit. prostate cancer (mHSPC) in adlt. men in combinat. with androgen depriv. ther.(ADT) and in combin. with prednisone.
C/I:  Hypersens./ by pregn. females or who may be potent. pregn../sev. hepat. impairm./ in combin. with Ra-223 if given with prednisone.

Androgen Biosynthesis Inhibitor. Abiraterone Acetate 250 mg.
Tab 120 X 250 mg
1000 mg/d (4 tab.), once/d in comb. with oral prednisone 5 mg (twice/d for metast. CRPC and once/d for High risk mHSPC)
In comb. with prednisone for tmt. of metast. castr.-resist. prostate cancer (CRPC)
newly diagn. high risk metast. hormone-sensit. prostate
cancer (mHSPC) in adlt men in comb. with androgen depriv. ther.(ADT).  
C/I: Hypersens./Women/Sev. liver damage/In comb. with Ra-223

Androgen Biosynthesis Inhibitor. Abiraterone Acetate 250 mg.
TABS: 120 x 250 mg. Recomm. dose
1000 mg (4 x 250 mg tab.) once dly in
comb. with prednisone. See lit.
CYP 17 inhibitor, in comb. with prednisone
for tmt. of pts. with metastatic castrationresist.
prostate cancer.
C/I: Hypersens.; Pregn.; Sev. hep. impair.
(Child-Pugh Class C).