5-HT1 Agonist

11 Drugs classified under this drug class

5-HT1 Agonist. Eletriptan (As Hydrobromide) 40 mg, 80 mg.
F.C. TABS: 3, 10x40 mg, 3x80 mg. Intend. for pts. over the age of 18 & under the age of 65. Can be taken at any stage after the migraine pain appears, but it is best to do so as soon as possible. The usual init. dose is 40 mg tab. If after the 1^st tab. ther is no relief, 2^nd tab. should not be taken for the same attack. If after a 1^st tab. the migraine is relieved and then comes back,  2^nd tab. may be taken. However there has to be at least 2 hrs. wait. before taking the 2^nd tab. See lit.
Acute tmt. of the headache phase of migraine attacks, with/without aura.
C/I: Hypersens. Cardiovascular disord. Pts. with hep./ren. impair. History/present moder.-severe hypertens. Pts. with mild untreat. hypertens. Pts. with history of CVA. Concom. use with ketoconazole, itraconazole (for treat. fung. infect.), erythromycin, clarithromycin, josamycin, ritonavir, indinavir, nelfinavir, and other 5HT1 serotonin receptor agon. Concom. use with ergot alkal. within 2 hrs before or after taking this drug. Pts. hereditary problem of intoler. to galactose, Lapp lactase defic., or impair. absorpt. of glucose/galactose.

5-HT1 Agonist. Sumatriptan (as succinate) 50 mg, 100 mg.
TABS: 2, 6 x 50 mg, 100 mg. 1 tab of 50
mg. Some pts. may require 1 tab of 100
mg. If sympt. recur: 1 tab. aft. at least 2
hrs. Pts. who fail to respond initially
should not receive second dose for
same attack. Max. dose: 3 tabs (300
mg) in 24 hrs.
Acute relief of migraine attacks, with or
w/o aura, should only be used where there
is a clear diagnosis of migraine.
C/I: Hypersens.; Pts. with hist. of MI or
have ischaem. heart dis., coron.
vasospasm (Prinzmetal’s ang.), periph. vasc. dis. or sympt. or signs consistent
with ischaem. heart dis.;
Pts. with a hist. of CVA or TIA; Pts. with
severe hep. impair.; Pts. with moder./
severe HTN. and mild uncontrol. HTN;
concom. admin.of ergotamine, or
derivate. of ergotamine (includ.
methysergide) or any triptan/5-HT1
receptor agon.; Concur. admin. with
MAOIs. Must not be used within 2 wks.
of discount. of ther. with MAOIs.

5-HT1 Agonist. Sumatriptan (as succinate) 6 mg / 0.5 ml.
PREFILL. SYRINGE: 2 x 6 mg / 0.5 ml
(incl. 1 auto-injector). 1 inject. S.C. If
sympt. recur in pt. who responds,
another inject. any time within next 24
hrs., but not less than 1 hr. aft. prev.
inject. Max. dose: 2 injects. (12 mg) in
24 hrs. Pts. who fail to respond initially
should not receive second dose for
same attack.
Acute relief of migraine attacks with or
w/o aure, cluster headache. For the acute
tmt. of migraine attacks assoc. with
women’s menstr. cycle.

5-HT1 Agonist. Sumatriptan 20 mg / 0.1 ml.
NASAL SPR.: 2 x 20 mg/0.1 ml. 1 x 2.
Up to 2 sprays in 24 hrs.
Acute tmt. of migraine attacks with or w/o
aura.
C/I: Hypersens.; Pts. with hist. of MI or
have ischaem. heart dis., coron.
vasospasm (Prinzmetal’s ang.), periph.
vasc. dis. or sympt. or signs consistent
with ischaem. heart dis.; Pts. with a hist. of CVA or TIA; Pts. with
severe hep. impair.; Pts. with moder./
severe HTN. and mild uncontrol. HTN;
concom. admin.of ergotamine, or
derivate. of ergotamine (includ.
methysergide) or any triptan/5-HT1
receptor agon.; Concur. admin. with
MAOIs. Must not be used within 2 wks.
of discount. of ther. with MAOIs.

5-HT1 Agonist. Naratriptan HCl 2.5 mg.
F.C. TABS: 2,4 x 2.5 mg. Adults (18-65 yrs.):
1 tab. as early as possib. after the
onset of a migraine; 2nd dose min. 4
hrs. aft. 1st dose.Up to 2 tabs.in 24 hrs.
Acute migraine, with or without aura.
C/I: Hypersens. Pts. with past MI or have
ischaem. heart dis., Prinzmetal’s angina/
coronary vasospasm, periph. vascular
dis. or pts. who have symp. or signs
consistent with ischaem. heart dis.
History of CVA, TIA. Pts. with moder.,
severe hypertens., mild uncontrol.
hypertens. Concom. use with
ergotamine, derivate or ergotamine
(including methysergide) or/and any
triptan/5-HT1 receptor agonist.

5-HT1 Agonist. Eletriptan (As Hydrobromide) 24.242, 48.485, 96.97 mg.
F.C.TABS: 3 x 20 mg, 40 mg, 80 mg;
10 x 40 mg. Initial: (18-65 yrs): 40 mg.
If inadequate incr. to 80 mg in
subsequent attack. If second dose
reqd: Not to be taken within 2 hrs. of
initial attack. Max. dly dose: Not to
exceed 160 mg. Use below 18 yrs not
recommend.
Acute tmt. headache phase migraine
attacks with/without aura.
C/I: Hypersens., within 24 hrs of tmt.
with another 5-HT1 agonist or
ergotamine cont., ergo-type medicat. or
methysergide, hemipleg. or basil
migraine, severe hepat./ren. impair.,
mod., severe or untreat. hypertens.,
confirm. coron. heart dis., incl. IHD,
Prinzmetals ang., signif. arrhyth. or heart
fail., periph. vasc. dis.,
history CVA or TIA.