All the Drug Class Drugs
2nd Generation Cephalosporins. Cefuroxime 750 mg. VIAL(Pwdr. for Sol. or susp. for inj./infus. IM/IV): 10×10ml. Adult.: Many infec. will respond to 750 mg ×3/d by IM or IV inj. For more severe infec., this dose should be incr. to 1.5 g ×3/d IV. The freq. of IM/ IV inj. can be incr. to six-hourly if necessary, giving total doses of 3g-6g dly.
Infant. & Child.: Doses of 30 -100 mg/kg/d given as three/four divided doses. A dose of 60 mg/kg/d will be appropriate for most infec.
Neonates: Doses of 30-100 mg/kg/d given as two/three divided doses. In the first wks. of life the serum half-life of cefuroxime can be three- five times that in adult. See lit.
Infec. caused by suscept. microorganisms, prophylaxis against post operat. infec. in a variety of operations.
C/I: Pts. with hypersens. to the cephalosporin antibiot.
2nd Generation Cephalosporins. Cefuroxime Sodium 750 mg/vial. VIALS: 10, 50. 750 mg 3 x dly I.M./I.V. inject. Severe infects: 1.5 g 3 x dly. Inf. and child: 30-100 mg/kg/day in 3-4 div.
doses. See lit.
Infects. upper and lower respir. tract,
bone and soft tissue, ear, nose and
throat, genito-urin. tract, gonorrh.,
meningit., proph. in surg. when incr. risk
of infect.
C/I: Hypersens. See lit.
2nd Generation Cephalosporins. Cefuroxime Sodium 750 mg. VIAL (pwdr for SOL for INJ/INF): 1 x 750
mg. I.M/ I.V use. Adjust accord. to pt’s age, weight, kind of infection and renal
function. See lit.
Adults, child. and neonates: Community
acquired pneumon., acute exacerbate. of
chronic bronchit., complicated UTIs,
includ. pyelonephrit., Soft-tissue
infect.:bcellulitis, erysipelas and wound
infect., intra-abdominal infect., prophyl.
against infection in GI (including
oesophageal), orthopaedic,
cardiovascular, and gynaecological
surgery (including caesarean
section).,nose infect. for examp,
sinusitis., septic arthritis.
C/I: Hypersens. to cefuroxime /
cephalosporin antibiotics/ beta-lactam
antibacterial agent (penicillins,
monobactams and carbapenems).
2nd Generation Cephalosporins. Cefuroxime (as axetil) 125 mg/5ml, 250 mg/5ml. SUSP: 50 ml x 125 mg/5 ml y; 50 ml,
100 ml x 250mg/5 ml. 10 mg 2 x dly aft.
food to max 250 mg/day. Serious
infects., otit. med: 15 mg/kg 2 x dly aft.
food. Most infects: 250 mg 2 x dly;
urinary tract infects: 125 mg 2 x dly:
Child: Most infects: 125 mg 2 x dly; otit.
med: 250 mg 2 x dly.
Infects. upper and lower respir. tract, urin.
tract, skin and soft tissue.
C/I: Hypersens. to cephalosporin. See lit.
2nd Generation Cephalosporins. Cefuroxime (as axetil) 125, 250, 500 mg. TABS: 10 x 125 mg y, 250 mg y, 500
mg y. Most infects: 250 mg 2 x dly.
Pneumonia: 500 mg 2 x dly. Urin. tract
infects: 125 mg 2 x dly. Uncomplicated
gonorrh: 1 g (single dose). Child: Most
infects: 125 mg 2 x dly. Otit. media: 250
mg 2 x dly. (Tabs. not to be chewed or
crushed, therefore not suitable for
child under 5 yrs.) To be taken aft. food.
Infects. upper and lower respir. tract, urin.
tract, skin and soft tissue.
C/I: Hypersens. to cephalosporin. See lit.
