Vinblastine Sulphate

1 Drug classified under this active ingredient

Vinca Alkaloid. Vinblastine Sulphate 1 mg/ml.
VIALS: 10 mg. I.V. inject. Initial: Adults:
Single dose 0.1 mg/kg (3.7 mg/m2) 1 x
wkly, follow. by leukocyte count. Child:
Single dose 2.5 mg/m2, follow. by
leukocyte count. Maint. ther., liver, ren.
funct. disords., combinat. ther: See lit.
Tmt. of follow. neoplasms, alone/in
conjunct. with other oncolyt. drugs: Freq.
respons. maligns: General. Hodgkin’s dis.
(stages III and IV, Ann Arbor modific. of Rye
staging system); non-Hodgkin’s
lymphoma, reticulum-cell sarcoma,
lymphosarcoma, mycosis fungoides,
neuroblastoma, Histiocytosis X. Less freq.
respons. maligns: Choriocarcinoma resist.
to other chemotherapeut. agents,
embryonal carcinoma of the testis,
carcinoma of the breast, unrespons. to
approp. endocrine surrg and hormonal
ther.
C/I: Hypersens. to vinblastine or other
vinca-alkaloids, excipients. Leukopen.
not relat. to tumor, severe uncontroll.
infect. Such infects. must first be
controll. with antiseptics/antibiotics bef.
admin. vinblastine, intrathecal admin.
vinblastine.