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  • Topotecan HCl
    2 Drugs classified under this active ingredient


    All the Active Ingredient Drugs

    Hycamtin Capsules
    Novartis
    RX
    partial basket chart
    Hycamtin Capsules

    Topoisomerase I Inhibitor. Topotecan HCl 0.25 mg, 1 mg.
    HARD CAPS: 10 x 0.25 mg, 1 mg. See lit.
    Tmt. pts with relapsed small cell lung
    cancer (SCLC) when re-tmt. with first-line
    regimen not approp.
    C/I: Severe hypersens., pregn., lact.,
    severe bone marrow depress. prior to
    start. 1st course (baseline neutrophils
    less than 1.5 x 10^9/L and/or placelet
    count less than 100 x 10^9/L.

    Hycamtin IV
    Novartis
    RX
    partial basket chart
    Hycamtin IV

    Topoisomerase I Inhibitor. Topotecan HCl 4 mg.
    VIAL (for infusion): 1. Dose must adjust.
    accord. to indication, blood counts and
    pt’s medical condit. See it.
    Metastat. carcinoma ovary where 1st -line
    or subsequent ther. failed, small cell lung
    cancer sens. dis. aft. fail. first line chemo.
    In comb. with cisplatin: Stage IV-B recur./
    persist. carcinoma cervix not amenable to
    curative tmt. with surg. and/or radiat.
    ther.
    C/I: Hypersens., lact., pts. already have
    severe bone marrow depress. prior to
    starting 1st course, as evidenced by
    baseline neutrophils < 1.5 x 109/l and/
    or a platelet count of <100 x 109/l.

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