All the Active Ingredient Drugs
MAOI-B Inhibitor. Rasagiline (as mesilate) 1 mg. TABS: 10, 30. 1 tab 1 x dly with/without
levodopa, with/without food. Elderly:
No dosage change. Child and
adolescents (under 18 yrs): Not
recommend. Hepat. impair: Severe:
Contraind., Mod: Avoid use; Mild: Use
with caution when initiat. ther. If pt.
progress. from mild to mod. hepat.
impair: Stop ther. Ren. impair: No
dosage change.
Idiopath. Parkinson’s dis. (PD) as
monother. (without levodopa) or as
adjunct. ther. (with levodopa) in pts.
with end of dose fluctuats.
C/I: Hypersens., concom. with other
MAOI’s or pethidine. At least 14 days
should elapse btw. discont. rasagiline
and initiat. MAOI’s or pethidine, severe
hepat. insuffic.
Monoamine Oxidase-β Inhibitor. Rasagiline 1mg. TABS.: 30.1mg×1/d. Not for use in pts. under 18 yrs. old.
Tmt. of idiopathic Parkinson's dis. (PD) as monother. (without levodopa) or as adjunct ther. (with levodopa) in pts. with end of dose fluctuat.
C/I: Hypersens. Concom. tmt. with other MAO inhib. (includ. med. and natural products without prescription e.g. St. John's Wort) or pethidine. At least 14 days must elapse between discount. of rasagiline and init. of tmt. with MAO inhib. or pethidine. Pts. with severe hep. impair.
