All the Active Ingredient Drugs
Statin. Pravastatin Sodium 10, 20, 40 mg. TABS: 30 x 10 mg, 20 mg,
40 mg. 10-40 mg dly at bedt.
Response within 1-2 wks. Max. effect.
4 wks. Elderly: Initiate at lower dose
and monitor.
Prim. prevent. coron. events: In
hypercholest. pts. to reduce risks of M.I.
revascularizat. and deaths due to CV
causes with no incr. in deaths from non-CV
causes. Second. prevent. CV events: In
hypercholesterolem. pts. incl. prior M.I. to
slow the progress. of coron. atheroscleros.
and reduce the risk of acute coron. events.
In pts. with prev. M.I. to reduce the risk of
recur. M.I., risk of myocard. revasc. proced.,
reduce the risk of stroke or transient
ischem. attacks. In hypercholesterolem.
and mixed dyslipidem. (Frederickson types
lla and llb): As adjunct to diet to reduce
elevat. total cholesterol, LDL - cholesterol
and triglyceride levels.
Statin. Pravastatin Sodium 20 mg, 40 mg. TAB: 30 x 20 mg,
40 mg. Usual dosage range: 10-40
mg dly at bedt. Dose response effect is
apparent within 1-2 wks; Max. effect: 4
wks. Perform periodic lipid determ. at
intervals of not less than 4 wks. and
adjust dosage. Not to be used under 18
yrs of age. Elderly and pts. with hepat.
or ren. impair: Initiate tmt. at the lower
dosage range and monitor pts.
Prim. prevent. coron. events: In
hypercholest. pts. to reduce risks of M.I..
revascularizat. and deaths due to CV causes
with no incr. in deaths from non-CV causes.
Second. prevent. CV events: In
hypercholesterolem. pts. incl. prior M.I. to
slow the progress. of coron. atheroscleros.
and reduce the risk of acute coron. events.
In pts. with prev. M.I. to reduce the risk of recur. M.I., risk of myocard. revasc. proced.,
reduce the risk of stroke or transient ischem.
attacks. In hypercholesterolem. and mixed
dyslipidem. (Frederickson types lla and llb):
As adjunct to diet to reduce elevat. total
cholesterol, LDL - cholesterol and
triglyceride levels.
C/I: Known hypersens. to any ingred.,
pregn., lact.; active liver dis. or
unexplained, persistent elevat. in liver
funct. tests.
