All the Active Ingredient Drugs
Antiplatelet Agent. Prasugrel 10 mg. FC tabs,14/28/30/56/60/ 90 X 10 mg
Adults:Prasugrel should be initiated with a single 60 mg loading dose and then contin. at 10 mg once/d. In UA/NSTEMI pts., where coronary angiography is performed within 48 hours after admission, loading dose should only be given at the time of PCI . Pts. taking this drug should also take ASA daily (75 mg to 325 mg).
In pts. with acute coronary syndr. (ACS) who are managed with PCI, premature discontinuat. of any antiplatelet agent, incl. this drug, could result in an incr. risk of thrombosis, myocardial infarct. or death due to the patient's underlying dis. A tmt. of up to 12 months is recomm. unless discontin. is clinically indicated.
Co-admin. with acetylsalicylic acid (ASA), for the prevention of atherothrombotic events in adult pts. with acute coronary syndr. (i.e. unstable angina, non-ST segment elevation myocardial infarct. [UA/NSTEMI] or ST segment elevation myocardial infarct. [STEMI]) undergoing primary or delayed percutaneous coronary intervention (PCI). The incr. efficacy should be balanced with the incr. risk in pts. with bleeding tendency, in those who had TIA/CVA in the past and in those above the age of 75 or weight below 60 kg.
C/I: Hypersens.
Active pathological bleeding/Hist. of stroke or transient ischaemic attack (TIA)/
Sev. hepatic impairm. (Child Pugh class C).
Antiplatelet Agent. Prasugrel 5, 10 mg. F.C. TABS.:28. 1 tab ×1/d. See lit.
Prasugrel Teva, co-admin. with acetylsalicylic acid (ASA), is indic. for the preven. of atherothrombotic events in pts. with acute coronary syndr. ( i.e. unstable angina, non-ST segment elevation MI [UA/NSTEMI] or ST segment elevation MI [STEMI] undergoing prim./ delayed percutaneous coronary intervent. (PCI).
The incr. efficacy should be balanced with the incr. risk in pts. with bleed. tendency in those who had TIA/CVA in the past and in those above the age of 75 or wt. below 60 kg.
C/I: Hypersens.
Pts. with active bleed. (e.g. bleed. ulcer in GI syst.).
Pts. with history of a stroke or a TIA.
Pts. with severe hep. dis.
