All the Active Ingredient Drugs
Immunostimulant. Mifamurtide 4 mg/vial. VIAL (pwdr. for concentrate. for dispers. for infus.): 1×4 mg. After reconstit. to final volum. of 50 ml, each ml of suspens. contains 0.08 mg mifamurtide.
Pts. 2-30 yrs.: 2 mg/m2 bdy. surf. As adjuvant ther. follow. resect.: twice wkly. at least 3 d apart for 12 wks., follow. by once wkly. tmts. for an addit. 24 wks. for a total of 48 infus in 36 wks. For special populat. See lit.
Tmt. in child., adolesc. & young adult. with. high grade, resectab., nonmetastat. osteosarcoma aft. macroscopic. Complete surg. resect. In combinat. with post-op. multi-agent chemother. Safety and effic. assessed in pts. 2-30 yrs at init. diagn.
C/I: Hypersens., Concurr. use with cyclosporine/other calcineurin inhibit., high-dose NSAIDs, cyclooxygenase inhibit.
