All the Active Ingredient Drugs
Thyroid Hormones. Levothyroxine Sodium 50 mcg, 100 mcg. TABS: 100. Initial: 50-100 μg dly, adjust
by 50 μg at 4-6 wk intervals until
normal metab. maintain. Pts > 50 yrs:
Initial: Max 50 μg dly. Cardiac dis: 25 μg
dly (as 50 μg on alternate days). See lit.
Hypothyroidism, cretinism, juvenile
myxoedema.
C/I: Hypersens., thyrotoxicos.
Thyroid Hormones. Levothyroxine Sodium 25 mcg, 50 mcg, 100 mcg. SCORED TABS: 100 x 25 μg, 100 x 50 μg, 100 x 100 μg.
Start with low dose, increase grad.
every 2-4 wks until full replace. dose
reached, see lit.
Benign euthyroid goitre, prophylax.
relapse aft. surgery for euthyroid goitre,
hypothyroidism., supp. ther. thyroid
cancer, during anti-thyroid drug tmt.,
diagnost. use, See lit.
C/I: Hypersens., untreated adrenal and/
or pituitary insuffic., untreat.
thyrotoxicos., acute MI, acute
myocarditis, acute pancarditis.
Combination therapy of levothyroxine and an antithyroid agent for hyperthyroidism is not indicated during pregnancy. See lit.
Thyroid Hormones. Levothyroxine Sodium 0.2 mg/ml. Sol. for IM inject./concentr. for sol for inf. 6X 0.2 mg/ ml
Myxdema coma:Doses vary depend. on the degree of hypothyroidism, subject’s age and indiv. toler. Daily admin. until the pt. is able to toler. an oral dose and is clin. stable. Initial loading dose of 500 micrograms on first day.
Maint. tmt. at a daily dose of 100 μg on average.
Replacement or supplem. ther. in congenital or acquired hypothyroidism of any etiology: Compl. hne. replacement ther. in adults requires 100 to 150 μg as a single daily dose, on average. To be establ. gradually and with caution: start with 25 μg /d, then incr. the daily dose by 25 μg at weekly intervals.
Once the dosage has been stable for a long enough period, repeat testing of thyroid hnes. levels. See full prescription info.
Myxedema coma/ Replacement or supplem. ther. in congenital or acquired hypothyroidism of any etiology
C/I: Hypersens. /Untreat. adrenal insuff.
Untreat. pituitary insuff./ Untreat. thyrotoxicosis.
Untreat. hypertension/ Acute MI
Acute myocarditis/ Acute pancarditis
Thyroid Hormones. Levothyroxine Sodium 50 mcg, 100 mcg. TABS: 90. The dose should be adjust.
based on clinic. response & lab. paramet.
Child: 0-3mths. 10-15 mcg/kg/d; 3-6 mths. 8-10 mcg/kg/d; 6-12 mths. 6-8 mcg/kg/d; 1-5 yrs. 5-6 mcg/kg/d; 6-12 yrs. 4-5 mcg/kg/d; over 12 yrs. but growth & puberty incomp. 1.7 mcg/kg/day based on clinic.response & lab.paramet.
Growth & puberty complete 1.7 mcg/
kg/d; Adult: 1.7 mcg/kg/d (100-125 mcg/d for a 70 kg adult).
Hypothyroidism. Pituitary TSH Suppres.
C/I: Hypersens., pts. with untreated
subclin. or overt thyrotoxicosis of any
etiology & pts. with acute MI., pts. with
uncorrect. adren. insuf.
