Lapatinib

1 Drug classified under this active ingredient

Tyrosine Kinase Inhibitor. Lapatinib (as ditosylate monohydrate) 250 mg.
F.C. TABS: 70. Adjust dose accord. to
indicat. and medical condit. Dose must
be taken once dly, at least 1 hr before or
after food. See lit.
In comb. with capecitabine, tmt. advanced/
metastat. breast cancer whose tumors
overexpress ErbB2 (HER2) who have
received prior ther. incl. anthracycline,
taxane and trastuzumab. In comb. with
letrozole for tmt. postmenopaus. women
with hormone recept. +ive metastat. breast
cancer that overexpress. HER2 recept. for
whom hormon. tmt. indicat. Tmt. in
combinat. with aromatase inhib. has not
been compared to trastuzumab-cont.
chemother. reg. for tmt. metastat. breast
cancer.
C/I: Hypersens.