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  • Imatinib
    2 Drugs classified under this active ingredient


    All the Active Ingredient Drugs

    Glivec
    Novartis
    RX
    partial basket chart
    Glivec

    Tyrosine Kinase Inhibitor. Imatinib 100 mg, 400 mg.
    F.C. TABS: 20, 60 x 100 mg; 10, 30 x
    400mg.
    Doses of 400 mg or 600 mg should be
    admin. once dly., whereas a daily dose
    of 800 mg should be admin. as 400 mg
    ×2/d in the morn. and even.
    Tmt. of adult pts. and child. 3 yrs. of age
    and above with Ph+ chron. myeloid
    leukaemia (Ph+ -CML) in chron. phase
    accelerat. phase or blast crisis. Glivec is
    also indicat. for the tmt. of adult pts.s
    with Kit (CD117) posit. unresect. and/or
    metastat. malignant GI strom. tumour.
    (GIST). Also indicated for the tmt. of :
    Adult pts. with newly diagnosed
    Philadelphia chromos. posit. acute
    lymphoblastic leukemia (Ph+ ALL) integrated with chemotherapy. Adult pts.
    with relapsed or refract. Ph + ALL as
    monother. Adult pts. with unresect.
    dermatofibrosarcoma protuberans
    (DFSP) and adult pts. with recurrent and/
    or metastat. DFSP who are not eligible
    for surg. Adult pts. with myelodyspiastic/
    myeloproliferative dis.(MDS/MPD) assoc.
    with PDGFR ( platelet - derived growth
    factor recept. ) gene re- arrangements.
    Adult pts. with hypereosinophilic syndr.
    (HES) and/or chronic eosinophilic
    leukaemia (CEL) who have the FIP1L1-
    PDGFRalfa fusion kinase (mutational
    analysis or FISH demonstration fo CHIC2
    allele deletion) and for pts. with HES and/
    or CEL who are FIP1L1-PDGFR alfa fusion
    kinase negative . Adult pts. with aggress.
    systemic mastocytosis (ASM) without the
    D816V c-kit mutation .Adjuvant tmt. of
    adult pts. follow. complete gross resec. of
    Kit (CD117) positive GIST.
    C/I: Hypersens.

    Imatinib
    Teva
    RX
    partial basket chart
    Imatinib

    Protein Kinase Inhibitor. Imatinib 100 mg, 400 mg.
    TABS: 60 ×100 mg, 30×400 mg.
    400 mg or 600 ×1/d, whereas a dly.
    dose of 800 mg should be administ. as
    400 mg ×2/d , in the morn. and in the
    even. Tmt. should be continued as long
    as the pt. cont. to benefit. should be
    administ. P.O. with meal and a large
    glass of water. See lit.
    Tmt. of adult pts. and child. ≥ 3yrs. with
    Ph+ -CML in chron. phase acceler. phase
    or blast crisi.. Tmt. of: Adult pts. with newly
    diagnosed Philadelphia chromosome
    posit. Ph+ ALL integrated with chemother..
    Adult pts. with relapsed or refractory Ph +
    ALL as monother. Adult pts. with unresec.
    DFSP and adult pts. with recur. and/or
    metast. DFSP who are not eligible for
    surgery. Adult pts. with MDS/MPD assoc.
    with PDGFR gene re- arrang.. Adult pts.
    with HES and/or CEL who have the FIP1L1-
    PDGFR alfa fusion kinase (mutational
    analysis or FISH demonst. for CHIC2 allele
    deletion) and for pts. with HES and/or CEL
    who are FIP1L1-PDGFR alfa fusion kinase
    negative . Adult pts. with ASM without the
    D816V c-kit mutation..
    C/I: Hypersens.

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