All the Active Ingredient Drugs
Gadobenic Acid 334 mg/ml. VIAL: 5, 10, 15, 20 ml/vial.
Liver: the recommended dose in adult
patients is 0.05 mmol/kg body weight.
This corresponds to 0.1 ml/kg of the 0.5
M solution. Brain and spine: the
recommended dose in adult and in
paediatric patients greater than 2 years
of age is 0.1 mmol/kg body weight. This
corresponds to 0.2 ml/kg of the 0.5 M
solution. MRA: the recommended dose in
adult patients is 0.1 mmol/kg body
weight. This corresponds to 0.2 ml/kg of
the 0.5 M solution. Breast: the
recommended dose in adult patients is
0.1 mmol/kg body weight. This
corresponds to 0.2 ml/kg of the 0.5 M
solution. For further information see lit.
Pediatric Population: No dosage
adjustment is considered necessary. Use
for MRI of the brain and spine is not
recommended in children less than 2
years of age. Use for MRI of the liver, MRI
of the breast or MRA is not
recommended in children less than 18
years of age. Other Special Populations:
See lit.
MultiHance is a paramagnetic contrast
agent for use in diagnostic magnetic
resonance imaging (MRI) indicated for:
MRI of the liver for the detection of focal
liver lesions in patients with known or
suspected primary liver cancer (eg.
hepatocellular carcinoma) or metastatic
disease; MRI of the brain and spine where it
improves the detection of lesions and
provides diagnostic information additional
to that obtained with unenhanced MRI;
Contrast-enhanced MR- angiography
where it improves the diagnostic accuracy
for detecting clinically significant stenoocclusive
vascular disease in patients with
suspected or known vascular disease of the
abdominal or peripheral arteries; MRI of
the breast, for the detection of malignant
lesions in patients where breast cancer is
known or suspected on the basis of
previous mammography or ultrasound
results.
C/I: Patients with hypersensitivity to the
active substance or to any of the
ingredients, patients with a history of
allergic or adverse reactions to other
gadolinium chelates. see lit.
