All the Active Ingredient Drugs
Estrogen Receptor Antagonist. Fulvestrant 250 mg / 5 ml. PREFILL. SYRINGE: 2. Adult females,
incl. elderly: 500 mg (2 consec. injects.)
monthly, admin. slow I.M. one in ea.
buttock. Addition. 500 mg dose 2 wks.
aft. init. dose. Child and adolesc: Not
recommend. as safety and efficacy not
established. Mild-mod. ren. impair: No
dose adjust. recommend. Safety and
efficacy not evaluated in severe ren.
impair. Mild-mod. hep. impair: Use
with caution. Safety and efficacy not
evaluated in hep. impair.
Tmt. postmenopaus. women with
estrogen receptor positive, locally
advanced or metastat. breast cancer for dis. relapse on or aft. adjuv. antiestrogen
ther.; or for dis. progress. on ther. with an
antiestrogen.
C/I: Known hypersens., pregn. lact.
Severe hep. impair.
