Daptomycin

2 Drugs classified under this active ingredient

Cyclic Lipopeptide. Daptomycin 500 mg/vial.
VIAL (lyophilized pwdr. for I.V. infus.): 1.
4 mg/kg I.V. infus. over 30 mins. in
0.9% sod. chlor. inject. once every 24
hours for 7-14 days. See lit.
Complicat. skin and skin structure
infects. caused by suscept. strains
Gram+ive microorgans., staphylococci,
streptococci, enterococous faecalis.
Comb. ther. when clin. indicated in
gram- tive/anerob. organs. Only to be
used when proven strongly suspect.
organs. due to suscept. bact. Not indicat.
tmt pneumon. See lit.
C/I: Known hypersens. See lit.

Antibiotics, Cyclic Lipopeptide. Daptomycin 500 mg.
1/5 vials :powder for sol. for inject. or inf.
4-6 mg/kg/d depending on indicat. See full prescription info.
- Complicated skin and skin structure infections  (cSSSI)
- cSSSI caused by susceptible isolates of the following Gram-pos. bacteria: Staphylococcus aureus (incl. methicillin-resistant isolates), Streptococcus pyogenes, Streptococcus agalactiae, Streptococcus dysgalactiae subsp. equisimilis, and Enterococcus faecalis (vancomycin-susceptible isolates only).
- Staphylococcus aureus Bloodstream Infect. (Bacteremia), incl. those with Right-Sided Infective Endocarditis, caused by Methicillin-Susceptible and Methicillin-Resistant Isolates Staphylococcus aureus bloodstream infect. (bacteremia), incl. those with right-sided infective endocarditis, caused by methicillin-susceptible and methicillin-resistant isolates.
- Combin. ther. may be indic. if the documented or presumed pathogens include Gram neg. or anaerobic organisms.
C/I:Hypersens.