Cobimetinib Hemifumarate

1 Drug classified under this active ingredient

Protein Kinase Inhibitor. Cobimetinib Hemifumarate 20 mg.
F.C. TABS.:63.
60 mg (3 tabs. of 20 mg) once dly., taken on a 28 day cycle. 21 consecutive d.  (1^st  -21^st day -tmt. period); follow.by a 7-day break (22^nd -28^th –tmt. break).  Each subseq. tmt. cycle should start after the 7-day tmt. break has elapsed. See lit.
Indicat.  for use in comb.  with vemurafenib for the tmt. of adult pts. with unresectab. or metastat. melanoma with a BRAF V600 mutation.
C/I: Hypersens.