All the Active Ingredient Drugs
Benzodiazepine. Clonazepam 0.5 mg, 2 mg. TABS: 30 x 0.5 mg, 2 mg. Initial: 0.25 mg
2 x dly. Incr. to 1 mg dly aft. 3 days.
Some pts. may benefit to max. 4 mg
dly. Not for pts. under 18 yrs. See lit.
Typical or atypical petit mal, Lenox
Gastaut syndr. (Petit mal variant),
generalized prim. or second. tonic-clonic
seizures incl. grand mal and focal
seizures, panic disord. with/without
C/I: Sens. to benzodiazepines, liver dis.,
acute narrow angle glaucoma, 1st.
Benzodiazepine. Clonazepam 2.5 mg/ml. ORAL DROPS: 10 ml.
Inf. /Child.:Init.dose up to 10 yrs. (or up
to 30 kg) 0.01-0.03 mg/kg daily given
in 2-3 divid. doses. The dose should be
incr. by no more than 0.25-0.5 mg
every 3rd day until either a dly.
mainten. dose of approx. 0.1 mg/kg of
bdy-wt. dly. has been reached or
seizures are controlled or side effect.
preclude further increase. Dly. max.
dose in child. is 0.2 mg/kg of bd-wgt
and shouldn’t be exceed.
Child.10-16 yrs.: init.dose is 1-1.5 mg/
day given in 2-3 divid. doses. May be
incr. by 0.25-0.5 mg every 3rd day until
the individ. mainten.dose (usually 3-6
mg/day) is reached. Adult.: init. dose shouldn’t exceed 1.5 mg/day divid.
into 3 doses. May be incr. in
increments of 0.5 mg every 3 days
until either seizures are adequately.
controlled or side effects preclude any
further incr.The mainten. dose must be
individual. for each pt. depend. upon
response. Usually a mainten. dose of
3-6 mg per day is sufficient. Max.
therap. dose for adults is 20 mg dly.
shouldn’t be exceed.
Epilepsy, panic disorder.
C/I: Hypersens. to benzodiazepines,
severe resp. insuff. ,severe. hepat. insuff,
acute narrow angle glaucoma.