All the Active Ingredient Drugs
Proteasome Inhibitor. Carfilzomib 60 mg/vial. SINGLE USE VIALS (Pwdr. for sol. for
inject.): I.V. over 2 to 10 min., on Days 1,
2, 8, 9, 15, 16, foll. by a rest period from
Days 17 to 28. Ea. 28day period is 1 tmt
cycle. In Cycle 1, a dose is 20 mg/m².
Dose must be indiv. adjust. accord.
with med. cond. and param. Modify
dos. based on toxic.
Tmt. of pts. with multiple myeloma who
have receiv. at least 2 prior ther. incl.
bortezomib and an immunomodul. ag.
and have demonstr. dis. progress. on or
within 60 days of compl. the last ther.
Appr. is based on response rate. Clinical
benefit, such as impr. in surv./sympt., has
not been verified.