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  • Carfilzomib
    1 Drug classified under this active ingredient

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    Proteasome Inhibitor. Carfilzomib 60 mg/vial.
    SINGLE USE VIALS (Pwdr. for sol. for
    inject.): I.V. over 2 to 10 min., on Days 1,
    2, 8, 9, 15, 16, foll. by a rest period from
    Days 17 to 28. Ea. 28day period is 1 tmt
    cycle. In Cycle 1, a dose is 20 mg/m².
    Dose must be indiv. adjust. accord.
    with med. cond. and param. Modify
    dos. based on toxic.
    Tmt. of pts. with multiple myeloma who
    have receiv. at least 2 prior ther. incl.
    bortezomib and an immunomodul. ag.
    and have demonstr. dis. progress. on or
    within 60 days of compl. the last ther.
    Appr. is based on response rate. Clinical
    benefit, such as impr. in surv./sympt., has
    not been verified.
    C/I: None.