All the Active Ingredient Drugs
Benzodiazepine. Alprazolam 0.25, 0.5, 1 mg. TABS: 30 x 0.25 mg, 0.5 mg, 1 mg.
For tmt .of anxiety: The tmt. will usually begin with one tab. of 0.25 mg or one tablet of 0.5 mg three times per day. Therefore, the dly. dosage is 0.75 mg - 1.5 mg. The dosage may be gradual. incr. (every 3-4 d. the dose may be incr. by 1 mg) up to a total dly. dosage of 3 mg, divid. throughout the day.
The dosage can be incr.to achieve a max. therap. effect, at intervals of 3-4 days, to a max. dly. dosage of 4 mg, given in divid. doses. For tmt. of panic: The tmt. will usually begin with 1 tab. of 0.5 mg ×3/d The dosage can be grad. incr., depend. on the response, (every 3-4 days the dose can be incr. by 1 mg) up to a dly. dosage greater than 4 mg, divided throughout the day. When the dosage needs to be incr., the common practice is to incr. the nighttime dosage first before incr. the daytime dosage.
Elderly or pts. suffering from fatigue: Init. 0.25 mg ×2,3/d. This dosage may be grad. incr.
Alpralid is intended for short-term use (no
more than 8-12 wks). See lit.
Tmt. of sympt. of tension & anxiety, anxiety accompan. by depress. and in panic states with/ without phobia.
C/I: Hypersens. to alprazolam or other benzodiazep.
Concom. use with antifungals e.g. ketoconazole, itraconazole.
Benzodiazepine. Alprazolam 0.25, 0.5, 1 mg. TABS: 50 x 0.25 mg, 0.5 mg, 1 mg. t.i.d. -
q.i.d. Individ. depend. on severity and
sympt.
Anx. states, mixed anx.-depress., panic
related disords.
C/I: Known hypersens. to compon. or
other benzodiazepines, narrow angle
glaucoma.
Benzodiazepine. Alprazolam 0.5, 1, 2 mg. E.R. TABS: 30 x 0.5 mg, 1 mg, 2 mg. Tabs. may be admin. once dly., preferab. in the morn. The tabs. should be taken intact; shouldn’t be chewed, crushed, or broken.
Anxiety: usual init. dose -1 mg dly. in one / two doses, usual dose range- 0.5 -4 mg dly., in one / two doses.
Depression: usual init. dose -1 mg dly. in one/ two doses, usual dose range, 0.5- 4.5 mg dly., in one /two doses.
Panic Disord.: usual init. dose - 0.5 to 1.0 mg given at bedt. or 0.5 mg ×2/d, usual dose range - dose should be adjust. to pt. response, with increm. no greater than 1 mg/d every 3 -4 days. See lit.
For the tmt. of anxiety and anxiety associat. with depress.
Tmt. of panic disord. with or without phobic avoidance.
C/I: Pts. with known hypersens. to alprazolam or other benzodiazepines.
Pts. taking strong cytochrome P450 3A (CYP3A) inhib. (e.g., ketoconazole, itraconazole), except ritonavir. See lit.