All the Active Ingredient Drugs
Protein Kinase Inhibitor. Afatinib (as dimaleate) 20, 30, 40, 50 mg. F.C TABS: 7, 14, 28 × 20 mg, 30 mg, 40
mg, 50 mg.
40 mg 1 x dly., 3 hrs. before meal and at
least 1 h. after. May incr. up to 50 mg 1 x
dly after 3 wks. without serious adverse
events. Tmt. should be cont. until dis.
progres. or until no longer tolerat. By
the pt. see lit.
As monother. for the tmt. of: EGFR TKInaïve
adult pts. with local. advanc. or
metastat. NSCLC with activat. EGFR
mutation(s); Local. advance. or metast.
NSCLC of squamous histology progress. on
or after platin. -based chemother.
C/I: Hypersens., pregnancy, lact.