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  • Pen-Rafa VK 500
    / Rafa


    Active Ingredient

    Status in Israel
    RX

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft

    Caplets

    40 x 500 mg

    full basket chart 88078 16780

    Dosage

    Streptococcal pharyngitis (“strep throat”): In Streptococcal pharyngitis the recommended dosage for adults is: 2 caplets of Pen-Rafa VK 500 in the morning (in total 1000 mg) and 2 caplets of Pen-Rafa VK 500 in the evening (in total 1000 mg), for 10 days. For children the recommended dosage is: 1 caplet of Pen-Rafa VK 500 in the morning and 1 caplet of Pen-Rafa VK 500 in the evening, for 10 days.
    Prophylaxis against bacterial endocarditis: In patients at high risk of acquiring bacterial endocarditis, when undergoing dental procedures or surgical procedures of the upper respiratory tract, the recommended dosage in adults and children over 25 kg bodyweight is: 4 caplets of Pen-Rafa VK 500 (in total 2000 mg) one hour before the procedure and 2 caplets of Pen-Rafa VK 500 (in total 1000 mg) 6 hours after the procedure.
    For other infections, the recommended dosage of Pen-Rafa VK 500 for adults and children above 12 years of age is: 1 caplet of Pen-Rafa VK 500, 4 times a day.
    For full details see prescribing information.


    Indications

    Penicillin V-K susceptible infections.


    Contra-Indications

    Hypersensitivity to penicillins, cephalosporins and penicillamine.


    Special Precautions

    Pregnancy: Should only be used if the benefits to the mother outweigh the potential hazards to the fetus.
    Lactation: Risk-benefit must be considered since use by nursing mother may lead to sensitization of the infant.
    Infants: With caution, particularly in neonates. In the treatment of GABHS infections, therapy should be continued for at least 10 days to help prevent the occurrence of acute rheumatic fever or glomerulonephritis.


    Side Effects

    Heartburn, diarrhea, nausea, sore mouth and tongue or a change in the color of the tongue, rash or itching, difficulty in breathing.


    Drug interactions

    Antidiarrheals, other antibiotics, oral contraceptives, probenecid, cyclosporins, methotrexate.


    Pregnancy and Lactation

    Pregnancy: Should only be used if the benefits to the mother outweigh the potential hazards to the fetus.
    Lactation: Risk-benefit must be considered since use by nursing mother may lead to sensitization of the infant.


    Manufacturer
    Sandoz GmbH, Austria

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