Cortisone Acetate

/ Rekah

See prescribing information for full details.

Conditions responding to corticosteroid therapy.

Systemic fungal infections unless specific anti-infective therapy is used.

In view of the potential of serious side effects and withdrawal problems, therapy should be carefully considered. High dose, short term therapy (1-3 days) can be withdrawn abruptly or slowly over 1 week. In therapy for more than one week, withdrawal should be conducted in a slow decremental fashion over several weeks. Even after cautious withdrawal, patients may need supplements during periods of stress. The lowest dose that can control the disease should be used. Steroid therapy in children necessitates careful consideration due to growth retard action. Pregnancy and lactation: Corticosteroids cross the placenta and have been associated with placental insufficiency, low birth weight and neonatal adrenal suppression. Adrenal function of the nursing infant may be affected.
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Depending on steroid, dose and length of treatment, glucocorticoid and mineralocorticoid side effects may be seen. These include suppression of growth in children, hypertension, sodium retention, GI effects, CNS disturbances, water retention, potassium loss, muscle weakness, aseptic necrosis of femoral and humeral heads, cushingoid changes, hyperglycemia, osteoporosis, depression, euphoria, peptic ulceration, posterior subcapsular cataracts, impaired wound healing, glaucoma with optical nerve damage, altered sperm motility, skin thinning, other skin reactions.
For full details see prescribing information.

See prescribing information for full details.