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  • Celcox
    / Trima


    Active Ingredient
    Celecoxib 100 mg, 200 mg

    Status in Israel
    RX

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft

    Capsules

    10 X 200 mg

    not in the basket chart 27394 3707

    Capsules

    20 X 100 mg

    not in the basket chart 27393 3706

    Related information


    Dosage

    Osteoarthritis: 200 mg, once daily, or 100 mg twice daily in divided doses.
    Rheumatoid arthritis: 100-200 mg twice daily, and in any case no more than 400 mg per day.


    Indications

    Symptomatic treatment of inflammation and pain in osteoarthritis, rheumatoid arthritis.


    Contra-Indications

    Hypersensitivity to components, syndrome of nasal polyps, angiodema, bronchospastic reactivity to aspirin or other NSAID agents, active peptic ulcer. Supps: for inflammatory lesions rectum of anus, or in patients with recent history rectal or anal bleed.


    Special Precautions

    Risk of GI ulceration, bleeding and perforation. Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue corticosteroids. Should not be administered to patients with aspirin sensitivity, use with caution in patients with pre-existing asthma. Pregnancy and lactation: NSAID’s are not recommended. Amounts excreted in breast milk with usual doses are considered too small to be harmful to the nursing infant.


    Side Effects

    Dizziness, abdominal pain, diarrhea, dyspepsia, flatulence.


    Drug interactions

    Flluconazole, antacids (aluminum magnesium). Lithium, coumarin anticoagulants, heparin, other NSAIDs, ketorolac. ACE inhibitors, thiazide diuretics, antihypertensives. Oral hypoglycemics, methotrexate, cardiac glycosides, spironolactone, corticosteroids, cimetidine, cyclosporin. Phenobarbitone, mifepristone, quinolones, potassium supplements, salt substitutes, phenylpropanolamine, sulphonamides, phenytoin, β-blockers.


    Manufacturer
    Trima Israel Pharmaceutical Products Maabarot Ltd. Israel
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